Here are a Selective questions of previous years questions papers collected by the different sources. this question papers are very helpful to all M. pharm IST Sem students.
Question -02 marks
- Enlist various types of bioassays.
- List the models for screening antileptics.
- Define Nootropics and name the models for evaluating anti-emetics.
- Compare interoceptive and exteroceptors anti-anxiety models.
- Categorize model for screening analgesics.
- Enlist three preclinical screening models of antidiabetics.
- Euthanasia of experimental animals.
- Methods of immunoassay.
- Carrageenan induced paw edema in Albino Wistar rats.
- Different strains and species of laboratory animals.
- Enlist two in-vitro preclinical screening models of antidepressants.
- Preclinical pharmacological screening models of hepatoprotective drugs.
- Anticancer agents.
- What do you mean by Test item in GLP?
- Which chemical is required for fusion of karyoplast with the enucleated cell?
- What is the role of Isoguvacine or muscimol in [ 3H]-GABA receptor binding assay for screening of GABAergic Compounds?
- Name the behavioral test used for assessing spatial learning.
- Which cell line is used for in-vitro NO release test (aphrodisiac activity)?
- Write down the principle of Konzett-Rossler method.
- Why aconitine used in preclinical screening of anti-arrhythmic agents? Write its mechanism of action.
- Enlist various models used for drug screening of non-insulin-dependent diabetes.
- Differentiate heterogeneous and homogenous immunoassay systems.
- What do you mean by micro-dosing studies?
- Write down about (in short) :-
- Euthanasia of experimental animals.
- Anesthetic agent of laboratory animals.
- CPCSEA
- Nootropics
- Immuno suppressants
- Objectives of Immunoassay.
- Insulin Limitations of animal experimentation
- Enlist three Preclinical pharmacological screening models of following
- Analgesics
- Anti -emetic
- Anti hypertensive
M. Pharm Question Paper (1st SEM)
Modern Pharmaceutical Analytical Techniques Question Paper
Question -10 marks
- Explain the in-vitro methods used for screening anti-cancer drugs.
- Discuss CPCSEA guidelines to conduct experiments on animals.
- What do you understand about maintenance and breeding of laboratory animals as well as also discuss about significance of Anesthesia on experimental animals?
- Explain in brief about Immunoassay methods its objective and preparation as well as evaluation for preclinical studies.
- Explain any two in-vitro methods for the preclinical screening of anti-epileptics.
- Discuss possible animal alternative models for preclinical screening of immunomodulators.
- Illustrate the preclinical screening models for evaluation of antidiabetics.
- Enlist different in-vitro and in-vivo preclinical screening models of nootropics. Explain any three in-vivo screening models.
- What is homogenous and heterogeneous immunoassay system? Discuss various methods and optimization of immunoassay.
- Discuss different preclinical pharmacological screening models for antiulcer agents.
Question -07 marks
- Explain the production and application of transgenic animals.
- Describe the methods used for screening anti-Parkinson drugs.
- Describe the CPCSEA guideline to conduct experiments on animals.
- Write about immunoassay for insulin.
- Describe different in-vivo preclinical screening models of anxiety.
- What are the main requirements of GLP (Good Laboratory Practice)?
- Discuss different methods used for the screening of sympathomimetic drugs.
- Explain any two in-vivo methods for the preclinical screening of anti-emetics.
- Write a note on in-vivo methods for the screening of anti-inflammatory agents.
- Illustrate any two methods for the preclinical screening of anti-atherosclerosis agents in detail.
- Name any five in-vivo models used for the screening of hepatoprotective agents. Explain any one in detail.
- Describe immunoassay for digoxin in detail.
- What do you mean by bioassay? Write its principle. Enlist various types of bioassay and their application.
- Write down preclinical screening of the Anti cancer agents using in vivo models.
- Discuss in detail about various routes of drug administration in experimental animals.
- Write down preclinical screening of the Anti diarrheal and laxatives using in vivo models.
- Write a note on commonly used experimental animals and other transgenic animal models.
- Write down in short about Hepatoprotective screening methods.
- Explain in brief about Maintenance and breeding of laboratory animals.
- Write down preclinical screening of the Parkinsonism using in vivo models.
- Explain in brief about effects of Anesthesia on experimental animals.
- What do you understand about preclinical screening of the Alzheimer disorder using in vitro animal models?
- Write down different in-vivo preclinical screening models for antifertility agents.
- Describe different in-vivo preclinical screening models of anti- atherosclerotic agents.
- Write about different methods of drug administration in laboratory animals.
- Discuss any two in-vitro screening methods of epilepsy.
- Discuss the animal models for screening anti-psychotics.
