Medicinal Chemistry-2 Question Paper

Here are a Most Important Question Medicinal Chemistry-II, (UNIT 1-5TH) (B.pharm 5TH semester) of previous years questions papers collected by the different sources. this question papers are very helpful to all b.pharm 5th sem students.

Question- 02 Marks

• Mention any two alkylating anticancer agents.
• Write the structure and use of minoxidine.
• Write the structure and use nitroglycerine.
• Write the structure and use of minoxidine and acetominadione.
• Write the structure and mechanism of action of triamterene.
• What are cardiac glycosides give their medicinal use.
• What are sex hormones? Write the structure of diethyl stilbesterol.
• Write the structure and IUPAC names of clopidogrel and captopril.
• What are osmotic diuretics? Give examples.
• Give the synthesis of meclorethamine.
• Write the structure and use of Diphenhydramine hydrochloride.
• Write the structure and use of triprolidine hydrochloride.
• Write the structure and use of cimetidine.
• Write the structure and use of isosorbide dinitrite.
• Write the structure and use of warfarin.
• How cyclophosphamide is activated after its administration.
• Write the synthesis and medicinal use of promethazine.
• Write the structure and use of timololand butaxaine.
• Sketch the synthesis route for benzocaine.
• What are steroids? Give examples.
• Write the structure and mechanism of action of cholestipol.
• Write the structure and use of sildenafil and ethacrynic acid.
• Write the structure and mechanism of action of nesiritide.
• What are beta blockers? Give any one structure of them.
• Write mechanism of action of 6-thioguanine.

Question- 07 Marks

• Discuss the chemistry and mechanism action of oral contraceptive agents.
• Write the SAR of Loop diuretics.
• What are antihyperlipidemic agents? Classify those giving examples.
• What are ACE inhibitors? Discuss their SAR and mechanism of action.
• Write a note on drugs used in erectile dysfunction.
• Discuss meglitinides with structure as antidiabetic agents.
• Write a note on drug used antihypertensive agents.
• Write the SAR of local anesthetics.
• Write a note on gastric proton pump inhibitors.
• Discuss the SAR of phenothiazine derivatives as antihistamine.
• Write the SAR of steroidal anti inflammatory agents.
• Write a note on thyroid and anti thyroid agents.
• What are anti coagulants? Write the synthesis and mechanism of action of warfarin.
• Explain the SAR of amino benzoic acid derivatives as local anesthetics.
• Explain the chemistry of piperazine class of anti- hostamine.

Question- 10 Marks

• Write the classification and SAR of antihistaminic agents. Add their clinical uses.
• What are local anesthetics? Write the SAR of them. Write the synthesis of procaine.
• Classify antidiabetics agnets with examples. Write the SAR and mechanism of action of thiazolidinediones.
• What are diuretics? Classify them with examples. Write the SAR of thiazide diuretics.
• Explain the SAR and mechanism of action of calcium channel blockers.
• Discuss the chemistry of male and female sex hormones.