Medicinal Chemistry-2 Question Paper

Here are a Most Important Question Medicinal Chemistry-II, (UNIT 1-5TH) (B.pharm 5TH semester) of previous years questions papers collected by the different sources. this question papers are very helpful to all b.pharm 5th sem students.

Question- 02 Marks

  • Mention any two alkylating anticancer agents.
  • Write the structure and use of minoxidine.
  • Write the structure and use nitroglycerine.
  • Write the structure and use of minoxidine and acetominadione.
  • Write the structure and mechanism of action of triamterene.
  • What are cardiac glycosides give their medicinal use.
  • What are sex hormones? Write the structure of diethyl stilbesterol.
  • Write the structure and IUPAC names of clopidogrel and captopril.
  • What are osmotic diuretics? Give examples.
  • Give the synthesis of meclorethamine.
  • Write the structure and use of Diphenhydramine hydrochloride.
  • Write the structure and use of triprolidine hydrochloride.
  • Write the structure and use of cimetidine.
  • Write the structure and use of isosorbide dinitrite.
  • Write the structure and use of warfarin.
  • How cyclophosphamide is activated after its administration.
  • Write the synthesis and medicinal use of promethazine.
  • Write the structure and use of timololand butaxaine.
  • Sketch the synthesis route for benzocaine.
  • What are steroids? Give examples.
  • Write the structure and mechanism of action of cholestipol.
  • Write the structure and use of sildenafil and ethacrynic acid.
  • Write the structure and mechanism of action of nesiritide.
  • What are beta blockers? Give any one structure of them.
  • Write mechanism of action of 6-thioguanine.

Question- 07 Marks

  • Discuss the chemistry and mechanism action of oral contraceptive agents.
  • Write the SAR of Loop diuretics.
  • What are antihyperlipidemic agents? Classify those giving examples.
  • What are ACE inhibitors? Discuss their SAR and mechanism of action.
  • Write a note on drugs used in erectile dysfunction.
  • Discuss meglitinides with structure as antidiabetic agents.
  • Write a note on drug used antihypertensive agents.
  • Write the SAR of local anesthetics.
  • Write a note on gastric proton pump inhibitors.
  • Discuss the SAR of phenothiazine derivatives as antihistamine.
  • Write the SAR of steroidal anti inflammatory agents.
  • Write a note on thyroid and anti thyroid agents.
  • What are anti coagulants? Write the synthesis and mechanism of action of warfarin.
  • Explain the SAR of amino benzoic acid derivatives as local anesthetics.
  • Explain the chemistry of piperazine class of anti- hostamine.

Question- 10 Marks

  • Write the classification and SAR of antihistaminic agents. Add their clinical uses.
  • What are local anesthetics? Write the SAR of them. Write the synthesis of procaine.
  • Classify antidiabetics agnets with examples. Write the SAR and mechanism of action of thiazolidinediones.
  • What are diuretics? Classify them with examples. Write the SAR of thiazide diuretics.
  • Explain the SAR and mechanism of action of calcium channel blockers.
  • Discuss the chemistry of male and female sex hormones.

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